Influence of passage number on the impact of the secretome of adipose tissue stem cells on neural survival, neurodifferentiation and axonal growth

Mesenchymal stem cells (MSCs), and within them adipose tissue derived stem cells (ASCs), have been shown to have therapeutic effects on central nervous system (CNS) cell populations. Such effects have been mostly attributed to soluble factors, as well as vesicles, present in their secretome. Yet, li...

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Veröffentlicht in:	Biochimie 2018-12, Vol.155, p.119-128
Hauptverfasser:	Serra, Sofia C., Costa, João C., Assunção-Silva, Rita C., Teixeira, Fábio G., Silva, Nuno A., Anjo, Sandro I., Manadas, Bruno, Gimble, Jeffrey M., Behie, Leo A., Salgado, António J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - cytology Adipose Tissue - metabolism Adipose tissue stem cells Animals Axonal growth Axons - metabolism Cell Culture Techniques - methods Cell Differentiation Central nervous system Differentiation Humans Proteomics Rats Rats, Wistar Secretome Stem Cells - cytology Stem Cells - metabolism
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