5-Nitrofuranes and 5-nitrothiophenes with anti- Trypanosoma cruzi activity and ability to accumulate squalene

Chagas disease represents a serious public health problem in South America. The first line of treatment is Nifurtimox and Benznidazole which generate toxic effects in treated patients. We have recently shown that a number of 5-nitrofuranes possess activity against Trypanosoma cruzi through oxidative...

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