Alcohol consumption and diabetes risk in a Chinese population: a Mendelian randomization analysis

Aim To assess the causality between alcohol intake, diabetes risk and related traits. Design Mendelian randomization (MR) study. Subgroup analysis, standard instrumental variable analysis and local average treatment effect (LATE) methods were applied to assess linear and non‐linear causality. Settin...

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Veröffentlicht in:	Addiction (Abingdon, England) England), 2019-03, Vol.114 (3), p.436-449
Hauptverfasser:	Peng, Miaomiao, Zhang, Jiaoyue, Zeng, Tianshu, Hu, Xiang, Min, Jie, Tian, Shenghua, Wang, Ying, Liu, Geng, Wan, Limin, Huang, Qiulan, Hu, Shengqing, Chen, Lulu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Alcohol Drinking - epidemiology Alcohol Drinking - genetics Alcohol use Alcoholic beverages Aldehyde dehydrogenase Aldehyde Dehydrogenase, Mitochondrial - genetics Alleles Asian Continental Ancestry Group - genetics Asian Continental Ancestry Group - statistics & numerical data Beta cells Causality China - epidemiology Chinese Diabetes Diabetes mellitus Diabetes Mellitus - epidemiology Fasting Female Females Glucose Health risk assessment Health risks Humans Insulin Insulin Resistance Insulin-Secreting Cells Male Males Men mendelian randomization Mendelian Randomization Analysis Middle Aged moderate drinking Population genetics Randomization Resistance Risk assessment Sex Factors U‐shaped relationship
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