Compound GDC, an Isocoumarin Glycoside, Protects against LPS-Induced Inflammation and Potential Mechanisms In Vitro

Compound 3 R -(4′-hydroxyl-3′-O-β-D-glucopyranosyl phenyl)-dihydro isocoumarin (GDC) is a natural isocoumarin, recently isolated from the stems of H. paniculiflorum. However, we know little about the effects of GDC on rheumatoid arthritis (RA). This study aims to investigate the protective effects a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Inflammation 2019-04, Vol.42 (2), p.506-515
Hauptverfasser:	Zhang, Yuqin, Yan, Guohong, Sun, Chengtao, Nan, Lihong, Wang, Xiaoying, Xu, Wei, Chu, Kedan
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Biomedical and Life Sciences Biomedicine c-Jun protein Ciliary neurotrophic factor Electron transport Enzyme-linked immunosorbent assay Extracellular signal-regulated kinase Fractalkine Glycosides Immunology Inflammation Interleukin 4 Interleukin 6 Internal Medicine JNK protein Kinases Lipopolysaccharides Mitochondria NF-κB protein Nitric oxide Nitric-oxide synthase Nuclear transport Original Article Pathology Pharmacology/Toxicology Phosphorylation Rheumatoid arthritis Rheumatology Rodents Signal transduction Synoviocytes Tissue inhibitor of metalloproteinase 1 Transcription factors Tumor necrosis factor-TNF γ-Interferon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!