Adaptation and limitation of anterior column reconstruction for pyogenic spondylitis in lower thoracic and lumbar spine

Surgical strategy for pyogenic spondylitis is controversial when vertebral body erosion is severe. Radical debridement and anterior column reconstruction is indicated for the purpose of early ambulatory to prevent secondary complication for long bed rest. However, such aggressive debridement and ris...

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Veröffentlicht in:Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2019-03, Vol.24 (2), p.219-223
Hauptverfasser: Nagata, Kosei, Ando, Takeshi, Nakamoto, Hideki, Kato, So, Sasaki, Katsuyuki, Oshima, Yasushi
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container_issue 2
container_start_page 219
container_title Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
container_volume 24
creator Nagata, Kosei
Ando, Takeshi
Nakamoto, Hideki
Kato, So
Sasaki, Katsuyuki
Oshima, Yasushi
description Surgical strategy for pyogenic spondylitis is controversial when vertebral body erosion is severe. Radical debridement and anterior column reconstruction is indicated for the purpose of early ambulatory to prevent secondary complication for long bed rest. However, such aggressive debridement and risk of perioperative complications are trade-off. The purpose of this study was to evaluate the risk factor of poor prognosis after anterior column debridement and reconstruction for pyogenic spondylitis in lower thoracic and lumbar spine. We performed a retrospective review of 40 patients diagnosed with pyogenic spondylitis in lower thoracic and lumbar spine who were introduced to our institution due to losing ambulatory ability and underwent anterior column debridement and reconstruction between January 2008 and May 2016. After the patient population was split into a regaining ambulatory group (Group A; n = 23) and a poor prognosis group (Group P; n = 17), we used Fisher exact tests and t-tests as appropriate for univariate analyses to compare patient characteristics and outcomes between the 2 groups. Univariate analysis showed that the significant variables were massive bleeding (>2000 ml) (P 
doi_str_mv 10.1016/j.jos.2018.09.011
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Radical debridement and anterior column reconstruction is indicated for the purpose of early ambulatory to prevent secondary complication for long bed rest. However, such aggressive debridement and risk of perioperative complications are trade-off. The purpose of this study was to evaluate the risk factor of poor prognosis after anterior column debridement and reconstruction for pyogenic spondylitis in lower thoracic and lumbar spine. We performed a retrospective review of 40 patients diagnosed with pyogenic spondylitis in lower thoracic and lumbar spine who were introduced to our institution due to losing ambulatory ability and underwent anterior column debridement and reconstruction between January 2008 and May 2016. After the patient population was split into a regaining ambulatory group (Group A; n = 23) and a poor prognosis group (Group P; n = 17), we used Fisher exact tests and t-tests as appropriate for univariate analyses to compare patient characteristics and outcomes between the 2 groups. Univariate analysis showed that the significant variables were massive bleeding (&gt;2000 ml) (P &lt; 0.01), Charlson Comorbidity Index ≥3 (P = 0.01), and two-stage surgery needed (P = 0.04). Logistic regression analysis showed that the factors associated with poor prognosis were massive bleeding (Odds Ratio 11.9; 95% confidence interval 1.8 to 119.7; P = 0.04). 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title Adaptation and limitation of anterior column reconstruction for pyogenic spondylitis in lower thoracic and lumbar spine
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