Repeated Restraint Stress Decreases Na,K-ATPase Activity via Oxidative and Nitrosative Damage in the Frontal Cortex of Rats

•Chronic restraint stress decreases α2,3-NKA activity in the frontal cortex.•Chronic restraint stress increases inflammation and membrane peroxidation in the frontal cortex.•iNOS and Cox-2 inhibition prevents the stress-induced inflammation, membrane peroxidation, and NKA impairment. Chronic psychog...

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Veröffentlicht in:	Neuroscience 2018-11, Vol.393, p.273-283
Hauptverfasser:	Novaes, Leonardo Santana, dos Santos, Nilton Barreto, Dragunas, Guilherme, Perfetto, Juliano Genaro, Leza, Juan Carlos, Scavone, Cristoforo, Munhoz, Carolina Demarchi
Format:	Artikel
Sprache:	eng
Schlagworte:	chronic stress frontal cortex neuroinflammation oxidative stress sodium pump
Online-Zugang:	Volltext
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