An Enantioconvergent and Concise Synthesis of Lasonolide A

Efficient access to medicinally significant natural products is an essential basis for the development of pharmaceuticals. The limited availability of marine natural products impedes broad biological evaluation. Despite several elegant syntheses of (−)‐lasonolide A having been reported, a practical...

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Veröffentlicht in:	Angewandte Chemie International Edition 2018-12, Vol.57 (49), p.16200-16204
Hauptverfasser:	Yang, Lin, Lin, Zuming, Shao, Shunjie, Zhao, Qian, Hong, Ran
Format:	Artikel
Sprache:	eng
Schlagworte:	Allyl compounds borane Chemical reactions Hydroboration macrolactonization Natural products olefination oxa-Michael reaction Oxidation Reagents Stereoselectivity Synthesis
Online-Zugang:	Volltext
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