Long non-coding RNA NEAT1 promotes colorectal cancer progression by competitively binding miR-34a with SIRT1 and enhancing the Wnt/β-catenin signaling pathway

In recent years, accumulating evidence has indicated that long non-coding RNAs (lncRNAs) are powerful factors influencing the progression of multiple malignancies. Although a relationship between the lncRNA NEAT1 (nuclear enriched abundant transcript 1) and colorectal cancer has previously been repo...

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Veröffentlicht in:	Cancer letters 2019-01, Vol.440-441, p.11-22
Hauptverfasser:	Luo, Yang, Chen, Jian-Jun, Lv, Qiang, Qin, Jun, Huang, Yi-Zhou, Yu, Min-Hao, Zhong, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer therapies Cell culture Cell proliferation Colorectal cancer Colorectal carcinoma Gene expression Medical prognosis Metastases Metastasis miR-34a miRNA Multivariate analysis NEAT1 Non-coding RNA Signal transduction SIRT1 SIRT1 protein Surgery Therapeutic applications Transcription Tumorigenesis Wnt protein Wnt/β-catenin signaling pathway β-Catenin
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