Periostin alters transcriptional profile in a rat model of isoproterenol-induced cardiotoxicity

Periostin is an extracellular matrix protein from the fasciclin family that guides cellular trafficking and extracellular matrix organization. Periostin stimulates mature cardiomyocytes to reenter the cell cycle. The molecular mechanism behind such stimulation remains to be explored. A DNA microarra...

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Veröffentlicht in:	Human & experimental toxicology 2019-02, Vol.38 (2), p.255-266
Hauptverfasser:	Sözmen, M, Devrim, AK, Kabak, YB, Devrim, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cardiomyocytes Cardiotoxicity Cell cycle Cell death Deoxyribonucleic acid DNA DNA chips DNA microarrays Extracellular matrix Fatty acids Gene expression Genes Isoproterenol Matrix protein Metabolism NF-κB protein Oxidative metabolism Oxidative phosphorylation Oxidative stress Phosphorylation Proteins Rodents Signal transduction Signaling Transcription Tumor necrosis factor-α
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