Individual Variability of Protein Expression in Human Tissues

Human tissues are known to exhibit interindividual variability, but a deeper understanding of the different factors affecting protein expression is necessary to further apply this knowledge. Our goal was to explore the proteomic variability between individuals as well as between healthy and diseased...

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Veröffentlicht in:	Journal of Proteome Research 2018-11, Vol.17 (11), p.3914-3922
Hauptverfasser:	Kushner, Irena K, Clair, Geremy, Purvine, Samuel Owen, Lee, Joon-Yong, Adkins, Joshua N, Payne, Samuel H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological Variation, Individual Biopsy Cell Line Data Mining - statistics & numerical data Female Gene Expression Profiling Gene Expression Regulation Humans Laser Capture Microdissection Liver - chemistry Machine Learning Male Monocytes - chemistry Organ Specificity Ovary - chemistry Pancreas - chemistry Peptides - chemistry Peptides - isolation & purification Peptides - metabolism Proteins - genetics Proteins - metabolism Proteomics - methods Retrospective Studies Single-Cell Analysis Substantia Nigra - chemistry Temporal Lobe - chemistry
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