Cannabinoid CB2-Selective Inverse Agonist Protects Against Antigen-Induced Bone Loss

Work to improve the therapeutic properties of cannabinoid CB2 receptor-selective inverse agonists has led to the development of Sch.036, an aryl substituted triaryl bis-sulfone with improved oral pharmacokinetic parameters. In this report, we show that this compound blocks in vivo trafficking of var...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Immunopharmacology and immunotoxicology 2007-01, Vol.29 (3-4), p.387-401
Hauptverfasser:	Lunn, Charles A., Fine, Jay, Rojas-Triana, Alberto, Jackson, James V., Lavey, Brian, Kozlowski, Joseph A., Hipkin, R. William, Lundell, Daniel J., Bober, Loretta
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Density Cannabinoid CB Chemotaxis Inverse Agonist Receptor Rheumatoid Arthritis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!