Post-Translational Tyrosine Geranylation in Cyanobactin Biosynthesis

Prenylation is a widespread modification that improves the biological activities of secondary metabolites. This reaction also represents a key modification step in biosyntheses of cyanobactins, a family of ribosomally synthesized and post-translationally modified peptides (RiPPs) produced by cyanoba...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Chemical Society 2018-05, Vol.140 (19), p.6044-6048
Hauptverfasser:	Morita, Maho, Hao, Yue, Jokela, Jouni K, Sardar, Debosmita, Lin, Zhenjian, Sivonen, Kaarina, Nair, Satish K, Schmidt, Eric W
Format:	Artikel
Sprache:	eng
Schlagworte:	analytical chemistry bioactive properties biosynthesis catalytic activity Cyanobacteria Cyanobacteria - chemistry Cyanobacteria - metabolism enzymology freshwater Geranyltranstransferase - isolation & purification Geranyltranstransferase - metabolism moieties peptides Peptides, Cyclic - biosynthesis Peptides, Cyclic - chemistry post-translational modification Protein Processing, Post-Translational regioselectivity secondary metabolites spectral analysis transferases tyrosine Tyrosine - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!