VSTM2A Overexpression Is a Sensitive and Specific Biomarker for Mucinous Tubular and Spindle Cell Carcinoma (MTSCC) of the Kidney

Our recent study revealed recurrent chromosomal losses and somatic mutations of genes in the Hippo pathway in mucinous tubular and spindle cell carcinoma (MTSCC). Here, we performed an integrative analysis of 907 renal cell carcinoma (RCC) samples (combined from The Cancer Genome Atlas and in-house...

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Veröffentlicht in:	The American journal of surgical pathology 2018-12, Vol.42 (12), p.1571-1584
Hauptverfasser:	Wang, Lisha, Zhang, Yuping, Chen, Ying-Bei, Skala, Stephanie L, Al-Ahmadie, Hikmat A, Wang, Xiaoming, Cao, Xuhong, Veeneman, Brendan A, Chen, Jin, Cieślik, Marcin, Qiao, Yuanyuan, Su, Fengyun, Vats, Pankaj, Siddiqui, Javed, Xiao, Hong, Sadimin, Evita T, Epstein, Jonathan I, Zhou, Ming, Sangoi, Ankur R, Trpkov, Kiril, Osunkoya, Adeboye O, Giannico, Giovanna A, McKenney, Jesse K, Argani, Pedram, Tickoo, Satish K, Reuter, Victor E, Chinnaiyan, Arul M, Dhanasekaran, Saravana M, Mehra, Rohit
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Mucinous - genetics Adenocarcinoma, Mucinous - pathology Adult Aged Aged, 80 and over Animals Biomarkers, Tumor - genetics Canada Carcinoma, Papillary - genetics Carcinoma, Papillary - pathology Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - pathology Diagnosis, Differential Female Gene Expression Regulation, Neoplastic Homeodomain Proteins - genetics Humans In Situ Hybridization Kidney Neoplasms - genetics Kidney Neoplasms - pathology Loop of Henle - chemistry Male Membrane Proteins - genetics Middle Aged Neoplasm Grading Predictive Value of Tests Rats Reproducibility of Results Transcription Factors - genetics Tumor Burden United States Up-Regulation Young Adult
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