Celecoxib Treatment Improves Neurologic Deficit and Reduces Selective Neuronal Loss and Glial Response in Rats after Transient Middle Cerebral Artery Occlusion

Areas of selective neuronal loss (SNL) represent the first morphologic signs of damage in the penumbra region and are considered putative targets for ischemic stroke therapy. We performed a novel assessment of measuring the effects of the anti-inflammatory agent celecoxib by analyzing simultaneously...

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Veröffentlicht in:The Journal of pharmacology and experimental therapeutics 2018-12, Vol.367 (3), p.528-542
Hauptverfasser: Santos-Galdiano, María, Pérez-Rodríguez, Diego, Anuncibay-Soto, Berta, Font-Belmonte, Enrique, Ugidos, Irene F., Pérez-García, Carlos César, Fernández-López, Arsenio
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Sprache:eng
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