Facile strategy involving low-temperature chemical cross-linking to enhance the physical and biological properties of hyaluronic acid hydrogel

•The cross-linking and degradation rates of HA were affected by the temperature.•Degradation rate of HA was more sensitive to the temperature than the cross-linking rate.•Mechanical Properties of the HA were markedly enhanced when it was fabricated at 10 °C.•HA hydrogels cross-linked at 10 °C exhibi...

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Veröffentlicht in:Carbohydrate polymers 2018-12, Vol.202, p.545-553
Hauptverfasser: Baek, Jaeuk, Fan, Yingfang, Jeong, Seol-Ha, Lee, Ho-Yong, Jung, Hyun-Do, Kim, Hyoun-Ee, Kim, Sukwha, Jang, Tae-Sik
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Sprache:eng
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