Clinical Significance of Extracellular Vesicles in Plasma from Glioblastoma Patients

Glioblastoma (GBM) is the most common primary brain tumor. The identification of blood biomarkers reflecting the tumor status represents a major unmet need for optimal clinical management of patients with GBM. Their high number in body fluids, their stability, and the presence of many tumor-associat...

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Veröffentlicht in:	Clinical cancer research 2019-01, Vol.25 (1), p.266-276
Hauptverfasser:	Osti, Daniela, Del Bene, Massimiliano, Rappa, Germana, Santos, Mark, Matafora, Vittoria, Richichi, Cristina, Faletti, Stefania, Beznoussenko, Galina V, Mironov, Alexandre, Bachi, Angela, Fornasari, Lorenzo, Bongetta, Daniele, Gaetani, Paolo, DiMeco, Francesco, Lorico, Aurelio, Pelicci, Giuliana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers, Tumor - blood Cell Line, Tumor Extracellular Vesicles - genetics Extracellular Vesicles - pathology Extracellular Vesicles - ultrastructure Female Glioblastoma - blood Glioblastoma - genetics Glioblastoma - pathology Heterografts Humans Male Mice Microscopy, Electron Neoplasm Recurrence, Local - blood Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology Prognosis Proteome - genetics
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