ε-MnO2-modified graphite electrode as a novel electrochemical sensor for the ultrasensitive detection of the newly FDA approved Hepatitis C antiviral drug ledipasvir

A novel, simple and sensitive electrochemical method for the determination of ledipasvir (LED), the newly FDA approved Hepatitis C antiviral drug was developed and validated using ε-MnO2-modified graphite electrode. Two different MnO2 polymorphs (γ- and ε-MnO2 nanoparticles) were synthesized and cha...

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Veröffentlicht in:	Analytica chimica acta 2018-12, Vol.1038, p.29-40
Hauptverfasser:	Abdel-aal, Fatma A.M., Rageh, Azza H., Said, Mohamed I., Saleh, Gamal A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Graphite electrode Harvoni® tablets Ledipasvir Oxidized ledipasvir Rat plasma samples ε- and γ-MnO2 nanoparticles
Online-Zugang:	Volltext
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