Enhancement of fear learning in PPARα knockout mice

•PPARα knockout mice showed enhanced fear learning.•Dopamine and its metabolites were increased in the amygdala of PPARα knockout mice.•The mRNA expression of dopamine-degrading enzymes was decreased in the amygdala of PPARα knockout mice.•Injection of a dopamine D1 receptor antagonist attenuated th...

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Veröffentlicht in:	Behavioural brain research 2019-02, Vol.359, p.664-670
Hauptverfasser:	Chikahisa, Sachiko, Chida, Daiki, Shiuchi, Tetsuya, Harada, Saki, Shimizu, Noriyuki, Otsuka, Airi, Tanioka, Daisuke, Séi, Hiroyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala Dopamine Fear learning PPARα
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