Targeting Tumor Microenvironment by Bioreduction-Activated Nanoparticles for Light-Triggered Virotherapy

Solid tumors characteristically display higher levels of lactate production due to anaerobic metabolism of glucose. Meanwhile, the U.S. Food and Drug Administration (FDA) has approved virotherapy for use in cancer treatment; however systemic administration remains as a particular challenge. Here we...

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Veröffentlicht in:ACS nano 2018-10, Vol.12 (10), p.9894-9902
Hauptverfasser: Tseng, S.-Ja, Kempson, Ivan M, Huang, Kuo-Yen, Li, Hsin-Jung, Fa, Yu-Chen, Ho, Yi-Cheng, Liao, Zi-Xian, Yang, Pan-Chyr
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Sprache:eng
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