A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis

Tissue-resident memory T cells (TRMs) are a novel nonvascular memory T cell subset. Although CD8 + TRMs are well-characterized, CD4 + TRMs—especially lung-resident memory Th17 cells—are still being defined. In this study, we characterized lung-resident memory Th17 cells (lung TRM17) and their role i...

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Veröffentlicht in:Mucosal immunology 2019, Vol.12 (1), p.265-276
Hauptverfasser: Ueno, Keigo, Urai, Makoto, Sadamoto, Sota, Shinozaki, Minoru, Takatsuka, Shogo, Abe, Masahiro, Otani, Yoshiko, Yanagihara, Nao, Shimizu, Kiminori, Iwakura, Yoichiro, Shibuya, Kazutoshi, Miyazaki, Yoshitsugu, Kinjo, Yuki
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Sprache:eng
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