Helicobacter pylori promotes hepatic fibrosis in the animal model

Helicobacter pylori infection has been reported to be very common in patients with chronic liver diseases, including cirrhosis. To elucidate the pathological effect of H. pylori infection on the progression of hepatic fibrosis, C57BL/6 mice and Sprague–Dawley rats were orally inoculated with H. pylo...

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Veröffentlicht in:	Laboratory investigation 2009-11, Vol.89 (11), p.1291-1303
Hauptverfasser:	Goo, Moon-Jung, Ki, Mi-Ran, Lee, Hye-Rim, Yang, Hai-Jie, Yuan, Dong-Wei, Hong, Il-Hwa, Park, Jin-Kyu, Hong, Kyung-Sook, Han, Jung-Youn, Hwang, Ok-Kyung, Kim, Dong-Hwan, Do, Sun-Hee, Cohn, Ronald D, Jeong, Kyu-Shik
Format:	Artikel
Sprache:	eng
Schlagworte:	16S rRNA Alanine Transaminase - blood Animals Aspartate Aminotransferases - blood Bacterial diseases Bacterial diseases of the digestive system and abdomen Biological and medical sciences Biomarkers - metabolism Biotechnology Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism Carbon Tetrachloride - toxicity Disease Progression Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Bacterial Helicobacter Infections - complications Helicobacter Infections - pathology Helicobacter pylori Helicobacter pylori - genetics Helicobacter pylori - pathogenicity hepatic fibrosis Human bacterial diseases Infectious diseases Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Investigative techniques, diagnostic techniques (general aspects) Laboratory Medicine liver Liver Cirrhosis, Experimental - blood Liver Cirrhosis, Experimental - microbiology Liver Cirrhosis, Experimental - pathology Medical sciences Medicine Medicine & Public Health Mice Mice, Inbred C57BL Pathology Rats Rats, Sprague-Dawley research-article RNA, Ribosomal, 16S - genetics senescence marker protein 30
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