Small potent ligands to the insulin-regulated aminopeptidase (IRAP)/AT4 receptor

Angiotensin IV analogs encompassing aromatic scaffolds replacing parts of the backbone of angiotensin IV have been synthesized and evaluated in biological assays. Several of the ligands displayed high affinities to the insulin‐regulated aminopeptidase (IRAP)/AT4 receptor. Displacement of the C‐termi...

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Veröffentlicht in:	Journal of peptide science 2007-07, Vol.13 (7), p.434-444
Hauptverfasser:	Axén, Andreas, Andersson, Hanna, Lindeberg, Gunnar, Rönnholm, Harriet, Kortesmaa, Jarkko, Demaegdt, Heidi, Vauquelin, Georges, Karlén, Anders, Hallberg, Mathias
Format:	Artikel
Sprache:	eng
Schlagworte:	adult neural stem cells angiotensin IV bioactive conformation insulin-regulated aminopeptidase IRAP peptide synthesis peptidemimetic structure-activity relationship turn mimetic
Online-Zugang:	Volltext
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