Dietary n-3 polyunsaturated fatty acids increase oxidative stress in rats with intracerebral hemorrhagic stroke

Abstract Intake of n-3 polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) has been suggested to associate with an increased risk of hemorrhagic stroke. The present study was designed to investigate the hypothesis that EPA and DHA increase oxidative stress...

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Veröffentlicht in:	Nutrition research (New York, N.Y.) N.Y.), 2009-11, Vol.29 (11), p.812-818
Hauptverfasser:	Park, Yongsoon, Nam, Somyoung, Yi, Hyeong-Joong, Hong, Hyun-Jong, Lee, Myoungsook
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals Behavior, Animal Biological and medical sciences Bleeding brain Brain - blood supply Brain - drug effects Brain - metabolism Deoxyguanosine - analogs & derivatives Deoxyguanosine - metabolism DHA Dietary Fats - metabolism Dietary Fats - pharmacology docosahexaenoic acid Docosahexaenoic Acids - metabolism Docosahexaenoic Acids - pharmacology Edema - metabolism eicosapentaenoic acid Eicosapentaenoic Acid - metabolism Eicosapentaenoic Acid - pharmacology EPA Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Gastroenterology and Hepatology glutathione Glutathione - metabolism hemorrhage Hemorrhage - metabolism hydroxydeoxyguanosine Intracerebral hemorrhagic stroke Intracranial Hemorrhages - metabolism Intracranial Hemorrhages - pathology Magnetic Resonance Imaging Male omega-3 fatty acids Oxidative stress Oxidative Stress - drug effects Rat Rats Rats, Sprague-Dawley risk factors stroke Stroke - metabolism Stroke - pathology superoxide dismutase Superoxide Dismutase - metabolism Thiobarbituric Acid Reactive Substances - metabolism thiobarbituric acid-reactive substances Vertebrates: anatomy and physiology, studies on body, several organs or systems
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