Chondrogenic differentiation of synovial fluid mesenchymal stem cells on human meniscus-derived decellularized matrix requires exogenous growth factors

[Display omitted] The objective of this study was to investigate whether meniscus-derived decellularized matrix (DCM) has the capacity to induce differentiation of synovial fluid-derived mesenchymal stem cells (SF-MSCs) towards a meniscus fibrochondrocyte (MFC) phenotype. The potential roles of tran...

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Veröffentlicht in:	Acta biomaterialia 2018-10, Vol.80, p.131-143
Hauptverfasser:	Liang, Yan, Idrees, Enaam, Szojka, Alexander R.A., Andrews, Stephen H.J., Kunze, Melanie, Mulet-Sierra, Aillette, Jomha, Nadr M., Adesida, Adetola B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggrecan Biocompatibility Biomedical materials Bone marrow Cadavers Cell culture Collagen Collagen (type X) Culture media Decellularized matrix Differentiation Extracellular matrix Freeze drying Growth factors Immunofluorescence Injuries Insulin Insulin-like growth factor I Knee Meniscus Mesenchymal stem cells Mesenchyme Morphology Osteoarthritis Pellets Phenotypes Repair Risk analysis Risk factors Scaffolds Scanning electron microscopy Scanning transmission electron microscopy Stem cells Synovial fluid Tissue engineering
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