In vitro analyses of the combination of high-dose doxycycline and antifungal agents against Candida albicans biofilms

Abstract The potential of antifungal agents used as antimicrobial lock therapy (ALT) for the conservative management of catheter-related candidemia has not been fully defined. We sought to determine the antifungal effect of high-dose doxycycline (DOX), alone or in combination with standard concentra...

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Veröffentlicht in:	International journal of antimicrobial agents 2009-10, Vol.34 (4), p.326-332
Hauptverfasser:	Miceli, Marisa H, Bernardo, Stella M, Lee, Samuel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal Agents - pharmacology Biofilms - drug effects Biological and medical sciences Candida albicans Candida albicans - drug effects Dose-Response Relationship, Drug Doxycycline - administration & dosage Doxycycline - pharmacology Drug Interactions Drug Therapy, Combination Echinocandins - pharmacology Fluconazole - pharmacology Humans Infectious Disease Lipopeptides Medical sciences Microbial Sensitivity Tests Pharmacology. Drug treatments
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