Efficient SB100X-directed transposition from non-integrating lentiviral vectors in primary human cells

Biological properties of the integration machinery of lentiviral vectors facilitate preferred insertion into actively transcribed genomic regions. We have previously shown that DNA circles generated during lentiviral transduction can serve as substrate for DNA transposition by a transiently expresse...

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Veröffentlicht in:	Human gene therapy 2009-11, Vol.20 (11), p.1508-1508
Hauptverfasser:	Moldt, B, Staunstrup, N, Bak, R, Sharma, N, Mates, L, Izsvak, Z, Ivics, Z, Mikkelsen, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Human immunodeficiency virus 1
Online-Zugang:	Volltext
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