Simultaneous voltammetric sensing of acetaminophen, epinephrine and melatonin using a carbon paste electrode modified with zinc ferrite nanoparticles

A highly selective electrochemical sensor was fabricated based on a modified carbon paste electrode with zinc ferrite nanoparticles (ZnFe 2 O 4 NPs). The nanocomposite has attractive properties such as high surface-to-volume ratio and good electrocatalytic activity towards the drugs acetaminophen (AC), epinephrine (EP), and melatonin (MT), best at working voltages of 0.35, 0.09 and 0.55 V (vs. Ag/AgCl), respectively. The linear ranges (and detection limits) are 6.5–135 (0.4) μmol L −1 for AC, 5–100 (0.7) μmol L −1 for EP, and 6.5–145 (3) μmol L −1 for MT. Graphical abstract A novel electrochemical sensor based on a modified carbon paste electrode with zinc ferrite nanoparticles (ZnFe 2 O 4 ) for the simultaneous detection of the acetaminophen, epinephrine and melatonin was fabricated