Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals
Purpose To investigate the visual impairment certification status in Japan. Study design Observational cross-sectional study. Methods We asked all welfare offices throughout Japan to submit data concerning age, sex, causative diseases, and visual impairment grades for newly certified visually impair...
Gespeichert in:
| Veröffentlicht in: | Japanese journal of ophthalmology 2019-01, Vol.63 (1), p.26-33 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 33 |
|---|---|
| container_issue | 1 |
| container_start_page | 26 |
| container_title | Japanese journal of ophthalmology |
| container_volume | 63 |
| creator | Morizane, Yuki Morimoto, Noriko Fujiwara, Atsushi Kawasaki, Ryo Yamashita, Hidetoshi Ogura, Yuichiro Shiraga, Fumio |
| description | Purpose
To investigate the visual impairment certification status in Japan.
Study design
Observational cross-sectional study.
Methods
We asked all welfare offices throughout Japan to submit data concerning age, sex, causative diseases, and visual impairment grades for newly certified visually impaired individuals aged ≥ 18 years in the fiscal year of 2015. The certification was based on criteria of the Act on Welfare of Physically Disabled Persons.
Results
In total, data were collected for 12,505 newly certified visually impaired individuals. The most common age group for these individuals was 80-89 years (29.6%), followed by 70-79 (26.3%) and 60-69 (17.3%) years. The most common causative disease was glaucoma (28.6%), followed by retinitis pigmentosa (14.0%), diabetic retinopathy (12.8%), and macular degeneration (8.0%). Glaucoma was the most common causative disease in both sexes (30.2% in men and 27.0% in women). The most common impairment grade was grade 2 (31.8%), followed by grades 5 (24.3%) and grade 1 (16.1%). The number of visually impaired individuals with underlying glaucoma had increased in comparison with the number in the most recent surveys (from fiscal years 2007 to 2009), whereas the number of individuals with underlying diabetic retinopathy and macular degeneration had decreased.
Conclusion
To our knowledge, this is the first nation-wide complete enumeration survey of newly certified visually impaired individuals in Japan. These findings may contribute to administrative activities concerning medical welfare as well as educational activities for preventing visual impairment. |
| doi_str_mv | 10.1007/s10384-018-0623-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2112614529</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2111962923</sourcerecordid><originalsourceid>FETCH-LOGICAL-c462t-1d2d19dbd4e381e4dbb5be87d6b6ffc8d586701382aa45cfbb58dd8d618ebb503</originalsourceid><addsrcrecordid>eNp1kc2KFDEUhYMoTjv6AG4k4MZNNDdJpVPuZPBnZMCNrkMquaUZqlJlUtVDv4jPa9pqFQRXN9zz3XMCh5CnwF8C5_tXBbg0inEwjGshmbpHdqBBMiGUvk92nAtgDTTNBXlUyi3nXAkpHpILyUXTyHa_Iz-uk48Bk0fqUqDerQULnXp6iGV1A43j7GIeMS00JvrRzS69pss3pH3MZaHJLXFK7K5aUD-N84ALUkzriPmXQsuaD3g8GSa8G47UY15iHzGcA-pqi6ibmEI8xFC35TF50NeBT87zknx59_bz1Qd28-n99dWbG-aVFguDIAK0oQsKpQFUoeuaDs0-6E73vTehMXrPQRrhnGp8X2UTggkaDNY3l5fkxeY75-n7imWxYyweh8ElnNZiBYDQoBrRVvT5P-jttOZUf3eioNWiFbJSsFE-T6Vk7O2c4-jy0QK3p9LsVpqtpdlTaVbVm2dn57UbMfy5-N1SBcQGlCqlr5j_Rv_f9Scx76WL</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2111962923</pqid></control><display><type>article</type><title>Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Morizane, Yuki ; Morimoto, Noriko ; Fujiwara, Atsushi ; Kawasaki, Ryo ; Yamashita, Hidetoshi ; Ogura, Yuichiro ; Shiraga, Fumio</creator><creatorcontrib>Morizane, Yuki ; Morimoto, Noriko ; Fujiwara, Atsushi ; Kawasaki, Ryo ; Yamashita, Hidetoshi ; Ogura, Yuichiro ; Shiraga, Fumio</creatorcontrib><description>Purpose
To investigate the visual impairment certification status in Japan.
Study design
Observational cross-sectional study.
Methods
We asked all welfare offices throughout Japan to submit data concerning age, sex, causative diseases, and visual impairment grades for newly certified visually impaired individuals aged ≥ 18 years in the fiscal year of 2015. The certification was based on criteria of the Act on Welfare of Physically Disabled Persons.
Results
In total, data were collected for 12,505 newly certified visually impaired individuals. The most common age group for these individuals was 80-89 years (29.6%), followed by 70-79 (26.3%) and 60-69 (17.3%) years. The most common causative disease was glaucoma (28.6%), followed by retinitis pigmentosa (14.0%), diabetic retinopathy (12.8%), and macular degeneration (8.0%). Glaucoma was the most common causative disease in both sexes (30.2% in men and 27.0% in women). The most common impairment grade was grade 2 (31.8%), followed by grades 5 (24.3%) and grade 1 (16.1%). The number of visually impaired individuals with underlying glaucoma had increased in comparison with the number in the most recent surveys (from fiscal years 2007 to 2009), whereas the number of individuals with underlying diabetic retinopathy and macular degeneration had decreased.
Conclusion
To our knowledge, this is the first nation-wide complete enumeration survey of newly certified visually impaired individuals in Japan. These findings may contribute to administrative activities concerning medical welfare as well as educational activities for preventing visual impairment.</description><identifier>ISSN: 0021-5155</identifier><identifier>EISSN: 1613-2246</identifier><identifier>DOI: 10.1007/s10384-018-0623-4</identifier><identifier>PMID: 30255397</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Age Distribution ; Aged ; Aged, 80 and over ; Blindness ; Certification ; Clinical Investigation ; Cross-Sectional Studies ; Diabetes ; Diabetes mellitus ; Diabetic retinopathy ; Enumeration ; Female ; Glaucoma ; Humans ; Impairment ; Incidence ; Japan - epidemiology ; Macular degeneration ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Ophthalmology ; People with disabilities ; Polls & surveys ; Retinitis ; Retinitis pigmentosa ; Retinopathy ; Retrospective Studies ; Surveys and Questionnaires ; Vision Disorders - epidemiology ; Vision Disorders - etiology ; Vision Disorders - physiopathology ; Visual Acuity ; Visual impairment ; Visual observation ; Visually Impaired Persons - statistics & numerical data</subject><ispartof>Japanese journal of ophthalmology, 2019-01, Vol.63 (1), p.26-33</ispartof><rights>Japanese Ophthalmological Society 2018</rights><rights>Japanese Journal of Ophthalmology is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c462t-1d2d19dbd4e381e4dbb5be87d6b6ffc8d586701382aa45cfbb58dd8d618ebb503</citedby><cites>FETCH-LOGICAL-c462t-1d2d19dbd4e381e4dbb5be87d6b6ffc8d586701382aa45cfbb58dd8d618ebb503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10384-018-0623-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10384-018-0623-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27922,27923,41486,42555,51317</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30255397$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Morizane, Yuki</creatorcontrib><creatorcontrib>Morimoto, Noriko</creatorcontrib><creatorcontrib>Fujiwara, Atsushi</creatorcontrib><creatorcontrib>Kawasaki, Ryo</creatorcontrib><creatorcontrib>Yamashita, Hidetoshi</creatorcontrib><creatorcontrib>Ogura, Yuichiro</creatorcontrib><creatorcontrib>Shiraga, Fumio</creatorcontrib><title>Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals</title><title>Japanese journal of ophthalmology</title><addtitle>Jpn J Ophthalmol</addtitle><addtitle>Jpn J Ophthalmol</addtitle><description>Purpose
To investigate the visual impairment certification status in Japan.
Study design
Observational cross-sectional study.
Methods
We asked all welfare offices throughout Japan to submit data concerning age, sex, causative diseases, and visual impairment grades for newly certified visually impaired individuals aged ≥ 18 years in the fiscal year of 2015. The certification was based on criteria of the Act on Welfare of Physically Disabled Persons.
Results
In total, data were collected for 12,505 newly certified visually impaired individuals. The most common age group for these individuals was 80-89 years (29.6%), followed by 70-79 (26.3%) and 60-69 (17.3%) years. The most common causative disease was glaucoma (28.6%), followed by retinitis pigmentosa (14.0%), diabetic retinopathy (12.8%), and macular degeneration (8.0%). Glaucoma was the most common causative disease in both sexes (30.2% in men and 27.0% in women). The most common impairment grade was grade 2 (31.8%), followed by grades 5 (24.3%) and grade 1 (16.1%). The number of visually impaired individuals with underlying glaucoma had increased in comparison with the number in the most recent surveys (from fiscal years 2007 to 2009), whereas the number of individuals with underlying diabetic retinopathy and macular degeneration had decreased.
Conclusion
To our knowledge, this is the first nation-wide complete enumeration survey of newly certified visually impaired individuals in Japan. These findings may contribute to administrative activities concerning medical welfare as well as educational activities for preventing visual impairment.</description><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Blindness</subject><subject>Certification</subject><subject>Clinical Investigation</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetic retinopathy</subject><subject>Enumeration</subject><subject>Female</subject><subject>Glaucoma</subject><subject>Humans</subject><subject>Impairment</subject><subject>Incidence</subject><subject>Japan - epidemiology</subject><subject>Macular degeneration</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Ophthalmology</subject><subject>People with disabilities</subject><subject>Polls & surveys</subject><subject>Retinitis</subject><subject>Retinitis pigmentosa</subject><subject>Retinopathy</subject><subject>Retrospective Studies</subject><subject>Surveys and Questionnaires</subject><subject>Vision Disorders - epidemiology</subject><subject>Vision Disorders - etiology</subject><subject>Vision Disorders - physiopathology</subject><subject>Visual Acuity</subject><subject>Visual impairment</subject><subject>Visual observation</subject><subject>Visually Impaired Persons - statistics & numerical data</subject><issn>0021-5155</issn><issn>1613-2246</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc2KFDEUhYMoTjv6AG4k4MZNNDdJpVPuZPBnZMCNrkMquaUZqlJlUtVDv4jPa9pqFQRXN9zz3XMCh5CnwF8C5_tXBbg0inEwjGshmbpHdqBBMiGUvk92nAtgDTTNBXlUyi3nXAkpHpILyUXTyHa_Iz-uk48Bk0fqUqDerQULnXp6iGV1A43j7GIeMS00JvrRzS69pss3pH3MZaHJLXFK7K5aUD-N84ALUkzriPmXQsuaD3g8GSa8G47UY15iHzGcA-pqi6ibmEI8xFC35TF50NeBT87zknx59_bz1Qd28-n99dWbG-aVFguDIAK0oQsKpQFUoeuaDs0-6E73vTehMXrPQRrhnGp8X2UTggkaDNY3l5fkxeY75-n7imWxYyweh8ElnNZiBYDQoBrRVvT5P-jttOZUf3eioNWiFbJSsFE-T6Vk7O2c4-jy0QK3p9LsVpqtpdlTaVbVm2dn57UbMfy5-N1SBcQGlCqlr5j_Rv_f9Scx76WL</recordid><startdate>20190101</startdate><enddate>20190101</enddate><creator>Morizane, Yuki</creator><creator>Morimoto, Noriko</creator><creator>Fujiwara, Atsushi</creator><creator>Kawasaki, Ryo</creator><creator>Yamashita, Hidetoshi</creator><creator>Ogura, Yuichiro</creator><creator>Shiraga, Fumio</creator><general>Springer Japan</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20190101</creationdate><title>Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals</title><author>Morizane, Yuki ; Morimoto, Noriko ; Fujiwara, Atsushi ; Kawasaki, Ryo ; Yamashita, Hidetoshi ; Ogura, Yuichiro ; Shiraga, Fumio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-1d2d19dbd4e381e4dbb5be87d6b6ffc8d586701382aa45cfbb58dd8d618ebb503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Age Distribution</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Blindness</topic><topic>Certification</topic><topic>Clinical Investigation</topic><topic>Cross-Sectional Studies</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetic retinopathy</topic><topic>Enumeration</topic><topic>Female</topic><topic>Glaucoma</topic><topic>Humans</topic><topic>Impairment</topic><topic>Incidence</topic><topic>Japan - epidemiology</topic><topic>Macular degeneration</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Ophthalmology</topic><topic>People with disabilities</topic><topic>Polls & surveys</topic><topic>Retinitis</topic><topic>Retinitis pigmentosa</topic><topic>Retinopathy</topic><topic>Retrospective Studies</topic><topic>Surveys and Questionnaires</topic><topic>Vision Disorders - epidemiology</topic><topic>Vision Disorders - etiology</topic><topic>Vision Disorders - physiopathology</topic><topic>Visual Acuity</topic><topic>Visual impairment</topic><topic>Visual observation</topic><topic>Visually Impaired Persons - statistics & numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morizane, Yuki</creatorcontrib><creatorcontrib>Morimoto, Noriko</creatorcontrib><creatorcontrib>Fujiwara, Atsushi</creatorcontrib><creatorcontrib>Kawasaki, Ryo</creatorcontrib><creatorcontrib>Yamashita, Hidetoshi</creatorcontrib><creatorcontrib>Ogura, Yuichiro</creatorcontrib><creatorcontrib>Shiraga, Fumio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Japanese journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morizane, Yuki</au><au>Morimoto, Noriko</au><au>Fujiwara, Atsushi</au><au>Kawasaki, Ryo</au><au>Yamashita, Hidetoshi</au><au>Ogura, Yuichiro</au><au>Shiraga, Fumio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals</atitle><jtitle>Japanese journal of ophthalmology</jtitle><stitle>Jpn J Ophthalmol</stitle><addtitle>Jpn J Ophthalmol</addtitle><date>2019-01-01</date><risdate>2019</risdate><volume>63</volume><issue>1</issue><spage>26</spage><epage>33</epage><pages>26-33</pages><issn>0021-5155</issn><eissn>1613-2246</eissn><abstract>Purpose
To investigate the visual impairment certification status in Japan.
Study design
Observational cross-sectional study.
Methods
We asked all welfare offices throughout Japan to submit data concerning age, sex, causative diseases, and visual impairment grades for newly certified visually impaired individuals aged ≥ 18 years in the fiscal year of 2015. The certification was based on criteria of the Act on Welfare of Physically Disabled Persons.
Results
In total, data were collected for 12,505 newly certified visually impaired individuals. The most common age group for these individuals was 80-89 years (29.6%), followed by 70-79 (26.3%) and 60-69 (17.3%) years. The most common causative disease was glaucoma (28.6%), followed by retinitis pigmentosa (14.0%), diabetic retinopathy (12.8%), and macular degeneration (8.0%). Glaucoma was the most common causative disease in both sexes (30.2% in men and 27.0% in women). The most common impairment grade was grade 2 (31.8%), followed by grades 5 (24.3%) and grade 1 (16.1%). The number of visually impaired individuals with underlying glaucoma had increased in comparison with the number in the most recent surveys (from fiscal years 2007 to 2009), whereas the number of individuals with underlying diabetic retinopathy and macular degeneration had decreased.
Conclusion
To our knowledge, this is the first nation-wide complete enumeration survey of newly certified visually impaired individuals in Japan. These findings may contribute to administrative activities concerning medical welfare as well as educational activities for preventing visual impairment.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>30255397</pmid><doi>10.1007/s10384-018-0623-4</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-5155 |
| ispartof | Japanese journal of ophthalmology, 2019-01, Vol.63 (1), p.26-33 |
| issn | 0021-5155 1613-2246 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2112614529 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Age Distribution Aged Aged, 80 and over Blindness Certification Clinical Investigation Cross-Sectional Studies Diabetes Diabetes mellitus Diabetic retinopathy Enumeration Female Glaucoma Humans Impairment Incidence Japan - epidemiology Macular degeneration Male Medicine Medicine & Public Health Middle Aged Ophthalmology People with disabilities Polls & surveys Retinitis Retinitis pigmentosa Retinopathy Retrospective Studies Surveys and Questionnaires Vision Disorders - epidemiology Vision Disorders - etiology Vision Disorders - physiopathology Visual Acuity Visual impairment Visual observation Visually Impaired Persons - statistics & numerical data |
| title | Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T12%3A21%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Incidence%20and%20causes%20of%20visual%20impairment%20in%20Japan:%20the%20first%20nation-wide%20complete%20enumeration%20survey%20of%20newly%20certified%20visually%20impaired%20individuals&rft.jtitle=Japanese%20journal%20of%20ophthalmology&rft.au=Morizane,%20Yuki&rft.date=2019-01-01&rft.volume=63&rft.issue=1&rft.spage=26&rft.epage=33&rft.pages=26-33&rft.issn=0021-5155&rft.eissn=1613-2246&rft_id=info:doi/10.1007/s10384-018-0623-4&rft_dat=%3Cproquest_cross%3E2111962923%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2111962923&rft_id=info:pmid/30255397&rfr_iscdi=true |