Chronic nonbacterial prostate inflammation in a rat model is associated with changes of gut microbiota that can be modified with a galactoglucomannan‐rich hemicellulose extract in the diet

Objectives To investigate dietary effects on the gut microbiota composition in a rat model of nonbacterial chronic prostate inflammation (CPI). Materials and methods Nonbacterial CPI was induced in the Wistar rat strain with subcutaneous testosterone and 17β‐oestradiol (E2) hormone pellets for 18 we...

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Veröffentlicht in:	BJU international 2019-05, Vol.123 (5), p.899-908
Hauptverfasser:	Konkol, Yvonne, Keskitalo, Anniina, Vuorikoski, Heikki, Pietilä, Sami, Elo, Laura L., Munukka, Eveliina, Bernoulli, Jenni, Tuomela, Johanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Animals Biodiversity Butyric acid chronic nonbacterial prostate inflammation Clostridiaceae Deoxyribonucleic acid Disease Models, Animal DNA Drinking water Feces - microbiology galactoglucomannan Gas chromatography Gastrointestinal Microbiome - drug effects Gastrointestinal Microbiome - physiology gut microbiota Hemicellulose Inflammation - drug therapy Inflammation - pathology Intestinal microflora Lipopolysaccharides lipopolysaccharide‐binding protein Male Mannans - pharmacology Microbiota Picea abies Polysaccharides - pharmacology Prostate Prostate - drug effects Prostate - pathology Prostatic Diseases - drug therapy Prostatic Diseases - pathology Rats Rats, Wistar Rodents rRNA 16S short‐chain fatty acid Testosterone
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