SURGICAL TREATMENT OF METASTATIC NON—FUNCTIONING NEUROENDOCRINE TUMORS OF THE PANCREAS

Experience of surgical treatment of 6 patients for synchronous and 9 — metachronous metastases of non—functioning neuroendocrine pancreas tumors (NEPT) in the liver was presented. In 14 (93.3%) patients made R0 resection. In 5 patients due synchronous metastases the combination intervention on pancreas and liver was performed, in one — limited to the removal of the primary tumor. Regarding synchronous metastasis in 8 patients resection of the liver, in 1 — multivisceral resection was performed. NEPT G2 stage diagnosed in 13 (86.7%) patients, neuroendocrine carcinoma G3 — in 2 (13.3%). Indications for surgical treatment of metastatic NEPT is resectable forms of the disease and the appearance of metastases is not earlier than 6 months after the first operation.