Bone marrow-derived mesenchymal stem cells ameliorate liver injury in a rat model of sepsis by activating Nrf2 signaling

Sepsis is a fatal condition that leads to serious systemic inflammation and multiple organ dysfunction syndromes. This study was designed to investigate the possible therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSCs) on sepsis-induced liver injury. We also aimed to examine the...

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Veröffentlicht in:	Histochemistry and cell biology 2019-03, Vol.151 (3), p.249-262
Hauptverfasser:	Selim, Sally A., El-Baset, Samia A. Abd, Kattaia, Asmaa A. A., Askar, Eman M., Elkader, Eman Abd
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis BAX protein Biochemistry Biomedical and Life Sciences Biomedicine Bone marrow Cell Biology Developmental Biology Glutathione peroxidase Hepatocytes Inflammation Interleukin 6 Lipopolysaccharides Liver Localization Mesenchymal stem cells Mesenchyme mRNA Original Paper Oxidative stress Proliferating cell nuclear antigen Regeneration Rodents Sepsis Stem cell transplantation Stem cells Tumor necrosis factor-α
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