Measuring fluorescence-lifetime and bio-impedance sensors for cell based assays using a network analyzer integrated circuit

Cell culture assays for therapeutic drug screening today are fully automated. Vitality of the cells is monitored by different sensors. For such a system, we propose a new reader unit, which is capable of reading two different fluorescent sensors and electrical impedance in 24-well-plates. Main goals...

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Veröffentlicht in:	Biosensors & bioelectronics 2019-03, Vol.129, p.292-297
Hauptverfasser:	Hefele, Markus, Wirths, Walter, Brischwein, Martin, Grothe, Helmut, Kreupl, Franz, Wolf, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	AD5933 Biosensing Techniques - instrumentation Cell Survival Dissolved oxygen measurement Drug Evaluation, Preclinical - instrumentation Electric Impedance Equipment Design Fluorescence measurement Humans Hydrogen-Ion Concentration Impedance measurement Live cell monitoring Oxygen - analysis Spectrometry, Fluorescence - instrumentation
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