Identification of amino acid residues critical for the B cell growth-promoting activity of HIV-1 matrix protein p17 variants

HIV-1 matrix protein p17 variants (vp17s) detected in HIV-1-infected patients with non-Hodgkin's lymphoma (HIV-NHL) display, differently from the wild-type protein (refp17), B cell growth-promoting activity. Biophysical analysis revealed that vp17s are destabilized as compared to refp17, motiva...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochimica et biophysica acta. General subjects 2019-01, Vol.1863 (1), p.13-24
Hauptverfasser:	He, Wangxiao, Mazzuca, Pietro, Yuan, Weirong, Varney, Kristen, Bugatti, Antonella, Cagnotto, Alfredo, Giagulli, Cinzia, Rusnati, Marco, Marsico, Stefania, Diomede, Luisa, Salmona, Mario, Caruso, Arnaldo, Lu, Wuyuan, Caccuri, Francesca
Format:	Artikel
Sprache:	eng
Schlagworte:	B cell proliferation HIV-1 Lymphoma Matrix protein p17 p17 clonogenic epitope p17 variants
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!