Distribution of DNA damage in the sperm nucleus: A study of zebrafish as a model of histone-packaged chromatin

Reproductive defects can occur when the integrity of the male gamete genome is affected. Sperm chromatin is not homogeneous, having relaxed regions which are more accessible to the transcription machinery in the embryo, and thought to be specially sensitive to DNA damage. The level of damage in spec...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Theriogenology 2018-12, Vol.122, p.109-115
Hauptverfasser:	González-Rojo, S., Fernández-Díez, C., Lombó, M., Herráez, M.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Cell Nucleus Chromatin - chemistry DNA Damage DNA Fragmentation Histones - metabolism Hydrogen Peroxide In Situ Nick-End Labeling Male Models, Genetic Sperm quality Spermatozoa - ultrastructure Zebrafish Zebrafish - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!