Oestradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in rats

We recently showed that male rats exhibit lower hypophagia and body weight loss compared to female rats following central leptin delivery, suggesting a role for oestradiol in leptin responsiveness. Accordingly, we delivered Ob (leptin) or GFP (control) gene into the brain of male rats that were simu...

Ausführliche Beschreibung