Pathophysiology and Individualized Treatment of Hypothalamic Obesity Following Craniopharyngioma and Other Suprasellar Tumors: A Systematic Review

Abstract The development of hypothalamic obesity (HO) following craniopharyngioma (CP) and other suprasellar tumors leads to reduced patient quality of life. No treatment algorithms are currently available for management of HO. Depending on which hypothalamic nuclei are destroyed, the pathophysiolog...

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Veröffentlicht in:	Endocrine reviews 2019-02, Vol.40 (1), p.193-235
Hauptverfasser:	van Iersel, Laura, Brokke, Karen E, Adan, Roger A H, Bulthuis, Lauren C M, van den Akker, Erica L T, van Santen, Hanneke M
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Brain Care and treatment Complications and side effects Development and progression Diet Energy expenditure Evidence-based medicine Health aspects Hyperinsulinemia Hyperphagia Hypopituitarism Hypothalamus Intervention Management Medical research Neoplasia Obesity Patients Physiological aspects Pituitary Pituitary tumors Quality of life Risk factors Signs and symptoms Sleep Sleep disorders Systematic review Tumors Weight control
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