The Burden of Sinusitis in Hematologic Transplant Patients: A National Perspective
Objectives/Hypothesis To determine the impact of sinusitis on outcomes of hematologic transplant procedures. Study Design Retrospective analysis of a national hospital database. Methods The National Inpatient Sample database for 2012 to 2013 was queried using International Classification of Diseases...
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| Veröffentlicht in: | The Laryngoscope 2018-12, Vol.128 (12), p.2688-2692 |
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| creator | Pandrangi, Vivek Reiter, Evan R. |
| description | Objectives/Hypothesis
To determine the impact of sinusitis on outcomes of hematologic transplant procedures.
Study Design
Retrospective analysis of a national hospital database.
Methods
The National Inpatient Sample database for 2012 to 2013 was queried using International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify patients undergoing hematologic transplants. Patients were divided based upon the presence or absence of a concomitant diagnosis of acute or chronic sinusitis. Patient demographics, clinical characteristics, discharge results, lengths of stay (LOS), and costs were compared between groups.
Results
There were 7,069 hematologic transplant cases identified, 2.7% of which had a diagnosis of sinusitis. Sinusitis patients had a longer LOS after transplant (24.9 ± 15.9 days vs. 19.1 ± 17.4 days, P |
| doi_str_mv | 10.1002/lary.27363 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2111153379</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2159953842</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3573-6a1c9fd5431bb3005da5927c3c4013f175f63714aed9d75c61fd8892517fa88d3</originalsourceid><addsrcrecordid>eNp9kEFLwzAUx4Mobk4vfgAJeBGhM-lrmsbbHOqEoWNO0FPJ0lQzunYmrbJvb2anBw--y3vw__Hn8UPomJI-JSS8KKRd90MOMeygLmVAg0gItou6PoQgYeFzBx04tyCEcmBkH3XAB0IkSRdNZ28aXzU20yWucvxoysaZ2jhsSjzSS1lXRfVqFJ5ZWbpVIcsaT2RtdFm7SzzA9_6uSlngibZupVVtPvQh2stl4fTRdvfQ0831bDgKxg-3d8PBOFDAOASxpErkGYuAzudACMskEyFXoCJCIaec5TFwGkmdiYwzFdM8SxIRMspzmSQZ9NBZ27uy1XujXZ0ujVO68E_qqnFpSP0wAC48evoHXVSN9X9vKOZlQRKFnjpvKWUr56zO05U1Sy83pSTdmE43ptNv0x4-2VY286XOftEftR6gLfBpCr3-pyodD6YvbekXjjOHhw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2159953842</pqid></control><display><type>article</type><title>The Burden of Sinusitis in Hematologic Transplant Patients: A National Perspective</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Pandrangi, Vivek ; Reiter, Evan R.</creator><creatorcontrib>Pandrangi, Vivek ; Reiter, Evan R.</creatorcontrib><description>Objectives/Hypothesis
To determine the impact of sinusitis on outcomes of hematologic transplant procedures.
Study Design
Retrospective analysis of a national hospital database.
Methods
The National Inpatient Sample database for 2012 to 2013 was queried using International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify patients undergoing hematologic transplants. Patients were divided based upon the presence or absence of a concomitant diagnosis of acute or chronic sinusitis. Patient demographics, clinical characteristics, discharge results, lengths of stay (LOS), and costs were compared between groups.
Results
There were 7,069 hematologic transplant cases identified, 2.7% of which had a diagnosis of sinusitis. Sinusitis patients had a longer LOS after transplant (24.9 ± 15.9 days vs. 19.1 ± 17.4 days, P < .001) and higher total hospital charges ($487,941 ± $447,532 vs. $322,300 ± $369,596, P < .001) than nonsinusitis patients. There was no difference in mortality between the two groups (P = .75). The 23 (12%) sinusitis patients who underwent sinus procedures had a longer LOS after transplant (34.8 ± 25 days vs. 23.5 ± 13.7 days, P = .001) and higher total hospital charges ($857,891 ± $718,456 vs. $437,293 ± $372,075, P < .001) than sinusitis patients without sinus procedures. Linear regression showed that sinusitis patients had excess LOS after transplant of 2.442 days and cost of $82,000.098.
Conclusions
This study demonstrates that presence of sinusitis in patients undergoing hematologic transplant is associated with increased LOS and higher total hospital charges. Increased focus on diagnosis and if possible treatment of sinusitis prior to admission for transplantation may help reduce the impact of sinusitis after hematologic transplant.
Level of Evidence
NA Laryngoscope, 128:2688–2692, 2018</description><identifier>ISSN: 0023-852X</identifier><identifier>EISSN: 1531-4995</identifier><identifier>DOI: 10.1002/lary.27363</identifier><identifier>PMID: 30239988</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Adult ; bone marrow transplant ; Chronic Disease ; Cost of Illness ; Databases, Factual ; Female ; hematopoietic stem cell transplant ; Hematopoietic Stem Cell Transplantation - adverse effects ; Hematopoietic Stem Cell Transplantation - economics ; Hospital Charges - statistics & numerical data ; Humans ; Length of Stay - economics ; Male ; Middle Aged ; Nose ; Postoperative Complications - economics ; Postoperative Complications - etiology ; Retrospective Studies ; Sinusitis ; Sinusitis - economics ; Sinusitis - etiology ; Stem cell transplantation ; Transplants & implants</subject><ispartof>The Laryngoscope, 2018-12, Vol.128 (12), p.2688-2692</ispartof><rights>2018 The American Laryngological, Rhinological and Otological Society, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3573-6a1c9fd5431bb3005da5927c3c4013f175f63714aed9d75c61fd8892517fa88d3</citedby><cites>FETCH-LOGICAL-c3573-6a1c9fd5431bb3005da5927c3c4013f175f63714aed9d75c61fd8892517fa88d3</cites><orcidid>0000-0003-1548-0441</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Flary.27363$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Flary.27363$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30239988$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pandrangi, Vivek</creatorcontrib><creatorcontrib>Reiter, Evan R.</creatorcontrib><title>The Burden of Sinusitis in Hematologic Transplant Patients: A National Perspective</title><title>The Laryngoscope</title><addtitle>Laryngoscope</addtitle><description>Objectives/Hypothesis
To determine the impact of sinusitis on outcomes of hematologic transplant procedures.
Study Design
Retrospective analysis of a national hospital database.
Methods
The National Inpatient Sample database for 2012 to 2013 was queried using International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify patients undergoing hematologic transplants. Patients were divided based upon the presence or absence of a concomitant diagnosis of acute or chronic sinusitis. Patient demographics, clinical characteristics, discharge results, lengths of stay (LOS), and costs were compared between groups.
Results
There were 7,069 hematologic transplant cases identified, 2.7% of which had a diagnosis of sinusitis. Sinusitis patients had a longer LOS after transplant (24.9 ± 15.9 days vs. 19.1 ± 17.4 days, P < .001) and higher total hospital charges ($487,941 ± $447,532 vs. $322,300 ± $369,596, P < .001) than nonsinusitis patients. There was no difference in mortality between the two groups (P = .75). The 23 (12%) sinusitis patients who underwent sinus procedures had a longer LOS after transplant (34.8 ± 25 days vs. 23.5 ± 13.7 days, P = .001) and higher total hospital charges ($857,891 ± $718,456 vs. $437,293 ± $372,075, P < .001) than sinusitis patients without sinus procedures. Linear regression showed that sinusitis patients had excess LOS after transplant of 2.442 days and cost of $82,000.098.
Conclusions
This study demonstrates that presence of sinusitis in patients undergoing hematologic transplant is associated with increased LOS and higher total hospital charges. Increased focus on diagnosis and if possible treatment of sinusitis prior to admission for transplantation may help reduce the impact of sinusitis after hematologic transplant.
Level of Evidence
NA Laryngoscope, 128:2688–2692, 2018</description><subject>Adult</subject><subject>bone marrow transplant</subject><subject>Chronic Disease</subject><subject>Cost of Illness</subject><subject>Databases, Factual</subject><subject>Female</subject><subject>hematopoietic stem cell transplant</subject><subject>Hematopoietic Stem Cell Transplantation - adverse effects</subject><subject>Hematopoietic Stem Cell Transplantation - economics</subject><subject>Hospital Charges - statistics & numerical data</subject><subject>Humans</subject><subject>Length of Stay - economics</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nose</subject><subject>Postoperative Complications - economics</subject><subject>Postoperative Complications - etiology</subject><subject>Retrospective Studies</subject><subject>Sinusitis</subject><subject>Sinusitis - economics</subject><subject>Sinusitis - etiology</subject><subject>Stem cell transplantation</subject><subject>Transplants & implants</subject><issn>0023-852X</issn><issn>1531-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFLwzAUx4Mobk4vfgAJeBGhM-lrmsbbHOqEoWNO0FPJ0lQzunYmrbJvb2anBw--y3vw__Hn8UPomJI-JSS8KKRd90MOMeygLmVAg0gItou6PoQgYeFzBx04tyCEcmBkH3XAB0IkSRdNZ28aXzU20yWucvxoysaZ2jhsSjzSS1lXRfVqFJ5ZWbpVIcsaT2RtdFm7SzzA9_6uSlngibZupVVtPvQh2stl4fTRdvfQ0831bDgKxg-3d8PBOFDAOASxpErkGYuAzudACMskEyFXoCJCIaec5TFwGkmdiYwzFdM8SxIRMspzmSQZ9NBZ27uy1XujXZ0ujVO68E_qqnFpSP0wAC48evoHXVSN9X9vKOZlQRKFnjpvKWUr56zO05U1Sy83pSTdmE43ptNv0x4-2VY286XOftEftR6gLfBpCr3-pyodD6YvbekXjjOHhw</recordid><startdate>201812</startdate><enddate>201812</enddate><creator>Pandrangi, Vivek</creator><creator>Reiter, Evan R.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1548-0441</orcidid></search><sort><creationdate>201812</creationdate><title>The Burden of Sinusitis in Hematologic Transplant Patients: A National Perspective</title><author>Pandrangi, Vivek ; Reiter, Evan R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3573-6a1c9fd5431bb3005da5927c3c4013f175f63714aed9d75c61fd8892517fa88d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>bone marrow transplant</topic><topic>Chronic Disease</topic><topic>Cost of Illness</topic><topic>Databases, Factual</topic><topic>Female</topic><topic>hematopoietic stem cell transplant</topic><topic>Hematopoietic Stem Cell Transplantation - adverse effects</topic><topic>Hematopoietic Stem Cell Transplantation - economics</topic><topic>Hospital Charges - statistics & numerical data</topic><topic>Humans</topic><topic>Length of Stay - economics</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nose</topic><topic>Postoperative Complications - economics</topic><topic>Postoperative Complications - etiology</topic><topic>Retrospective Studies</topic><topic>Sinusitis</topic><topic>Sinusitis - economics</topic><topic>Sinusitis - etiology</topic><topic>Stem cell transplantation</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pandrangi, Vivek</creatorcontrib><creatorcontrib>Reiter, Evan R.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The Laryngoscope</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pandrangi, Vivek</au><au>Reiter, Evan R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Burden of Sinusitis in Hematologic Transplant Patients: A National Perspective</atitle><jtitle>The Laryngoscope</jtitle><addtitle>Laryngoscope</addtitle><date>2018-12</date><risdate>2018</risdate><volume>128</volume><issue>12</issue><spage>2688</spage><epage>2692</epage><pages>2688-2692</pages><issn>0023-852X</issn><eissn>1531-4995</eissn><abstract>Objectives/Hypothesis
To determine the impact of sinusitis on outcomes of hematologic transplant procedures.
Study Design
Retrospective analysis of a national hospital database.
Methods
The National Inpatient Sample database for 2012 to 2013 was queried using International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify patients undergoing hematologic transplants. Patients were divided based upon the presence or absence of a concomitant diagnosis of acute or chronic sinusitis. Patient demographics, clinical characteristics, discharge results, lengths of stay (LOS), and costs were compared between groups.
Results
There were 7,069 hematologic transplant cases identified, 2.7% of which had a diagnosis of sinusitis. Sinusitis patients had a longer LOS after transplant (24.9 ± 15.9 days vs. 19.1 ± 17.4 days, P < .001) and higher total hospital charges ($487,941 ± $447,532 vs. $322,300 ± $369,596, P < .001) than nonsinusitis patients. There was no difference in mortality between the two groups (P = .75). The 23 (12%) sinusitis patients who underwent sinus procedures had a longer LOS after transplant (34.8 ± 25 days vs. 23.5 ± 13.7 days, P = .001) and higher total hospital charges ($857,891 ± $718,456 vs. $437,293 ± $372,075, P < .001) than sinusitis patients without sinus procedures. Linear regression showed that sinusitis patients had excess LOS after transplant of 2.442 days and cost of $82,000.098.
Conclusions
This study demonstrates that presence of sinusitis in patients undergoing hematologic transplant is associated with increased LOS and higher total hospital charges. Increased focus on diagnosis and if possible treatment of sinusitis prior to admission for transplantation may help reduce the impact of sinusitis after hematologic transplant.
Level of Evidence
NA Laryngoscope, 128:2688–2692, 2018</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>30239988</pmid><doi>10.1002/lary.27363</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-1548-0441</orcidid></addata></record> |
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| subjects | Adult bone marrow transplant Chronic Disease Cost of Illness Databases, Factual Female hematopoietic stem cell transplant Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - economics Hospital Charges - statistics & numerical data Humans Length of Stay - economics Male Middle Aged Nose Postoperative Complications - economics Postoperative Complications - etiology Retrospective Studies Sinusitis Sinusitis - economics Sinusitis - etiology Stem cell transplantation Transplants & implants |
| title | The Burden of Sinusitis in Hematologic Transplant Patients: A National Perspective |
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