Pd(II) and Pt(II) saccharinate complexes of bis(diphenylphosphino)propane/butane: Synthesis, structure, antiproliferative activity and mechanism of action

[M(sac)2(dppp)] (1 and 2), [M(dppp)2](sac)2 (3 and 4) and [M(sac)2(dppb)] (5 and 6) complexes, where M = PdII (1, 3 and 5) and PtII (2, 4 and 6), sac = saccharinate, dppp = 1,3-bis(diphenylphosphino)propane and dppb = 1,4-bis(diphenylphosphino)butane, were synthesized and characterized by IR, NMR, E...

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Veröffentlicht in:	European journal of medicinal chemistry 2018-10, Vol.158, p.534-547
Hauptverfasser:	Yilmaz, Veysel T., Icsel, Ceyda, Aygun, Muhittin, Erkisa, Merve, Ulukaya, Engin
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 lung cancer cell Anticancer mechanism Bis(diphenylphosphino)propane/butane HCT116 colon cancer cell Pd(II) and Pt(II) Saccharinate
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