Increased levels of soluble co-stimulatory molecule PD-L1 (B7-H1) in the plasma of viraemic HIV-1+ individuals

•We report the increment of sPD-L1 in plasma of viremic HIV + individuals.•sPD-L1 in viremic HIV + individuals correlate with plasma sCD14.•sPD-L1 in viremic HIV + individuals correlate with mPD-L1 present on blood conventional dendritic cells.•In vitro experiments described that Mo-DCs produce sPD-...

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Veröffentlicht in:	Immunology letters 2018-11, Vol.203, p.70-79
Hauptverfasser:	León-Flores, A., Del Río Estrada, P.M., Álvarez-García, L.X., Piten-Isidro, E., Reyes-Terán, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult B7-H1 Antigen - immunology Dendritic Cells - immunology Dendritic Cells - pathology Female HIV infection HIV Infections - immunology HIV Infections - pathology HIV-1 - immunology Humans Inflammation markers LPS Male Middle Aged MMP MO-DC Monocytes - immunology Monocytes - pathology Soluble programmed death ligand 1 (sPD-L1) Tumor Necrosis Factor-alpha - immunology Viremia - immunology Viremia - pathology
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