The role of orphan G protein-coupled receptors in the modulation of pain: A review

G protein-coupled receptors (GPCRs) comprise a large number of receptors. Orphan GPCRs are divided into six families. These groups contain orphan receptors for which the endogenous ligands are unclear. They have various physiological effects in the body and have the potential to be used in the treat...

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Veröffentlicht in:	Life sciences (1973) 2018-11, Vol.212, p.59-69
Hauptverfasser:	Nourbakhsh, Fahimeh, Atabaki, Rabi, Roohbakhsh, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesia Analgesics Animals Anti-inflammatory agents Dependence Drugs G protein-coupled receptors GPR55 Humans Inflammation Ligands Medical treatment Modulation Nervous system Nonsteroidal anti-inflammatory drugs Opioids Orphan GPCRs Orphan receptors Orphans Pain Pain - physiopathology Peripheral nervous system Peripheral neuropathy Physiological effects Physiological psychology Proteins Receptors Receptors, G-Protein-Coupled - metabolism Reviews Rodents Side effects
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