A new lipidomics approach by thin-layer chromatography-blot-matrix-assisted laser desorption/ionization imaging mass spectrometry for analyzing detailed patterns of phospholipid molecular species

Thin-layer chromatography (TLC) is a highly established convenient technique for lipid separation and partial characterization of neutral and acidic glycosphingolipids (GSLs) and phospholipids, in mixtures. Meanwhile, imaging mass spectrometry (IMS) is a promising tool for lipidomics. However, some...

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Veröffentlicht in:	Journal of Chromatography A 2009-10, Vol.1216 (42), p.7096-7101
Hauptverfasser:	Goto-Inoue, Naoko, Hayasaka, Takahiro, Taki, Takao, Gonzalez, Tania Valdes, Setou, Mitsutoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Brain Chemistry Chromatography, Thin Layer - methods Computational Biology - methods Humans Imaging Investigative techniques, diagnostic techniques (general aspects) Linear Models Lipidomics MALDI Medical sciences Miscellaneous. Technology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Phospholipids - chemistry Phospholipids - isolation & purification Reproducibility of Results Sensitivity and Specificity Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods TLC-Blot
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