Revealing the metabolic characteristics of human embryonic stem cells by genome‐scale metabolic modeling

Embryonic stem cells (ESCs) are characterized by a dual capacity, self‐renewal and pluripotency, which can be regulated by metabolism. A better understanding of ESC metabolism and regulatory mechanisms is pivotal for research into development, ageing, and cancer treatment. However, a systematic and...

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Veröffentlicht in:	FEBS letters 2018-11, Vol.592 (22), p.3670-3682
Hauptverfasser:	He, Yangzhige, Wang, Yan, Zhang, Boya, Li, Yang, Diao, Lihong, Lu, Liang, Yao, Jingwen, Liu, Zhongyang, Li, Dong, He, Fuchu
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid deprivation essential metabolites genome‐scale metabolic models human embryonic stem cells network motifs
Online-Zugang:	Volltext
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