Simulation of the nodal flow of mutant embryos with a small number of cilia: comparison of mechanosensing and vesicle transport hypotheses

Left–right (L-R) asymmetry in the body plan is determined by nodal flow in vertebrate embryos. Shinohara et al. (Shinohara K et al. 2012 Nat. Commun. 3, 622 (doi:10.1038/ncomms1624)) used Dpcd and Rfx3 mutant mouse embryos and showed that only a few cilia were sufficient to achieve L-R asymmetry. Ho...

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Veröffentlicht in:	Royal Society open science 2018-08, Vol.5 (8), p.180601-180601
Hauptverfasser:	Omori, Toshihiro, Winter, Katja, Shinohara, Kyosuke, Hamada, Hiroshi, Ishikawa, Takuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry And Biophysics Boundary Element Method Fluid–structureinteraction Left–right Asymmetry Nodal Flow
Online-Zugang:	Volltext
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