Induction of Hepatic Metabolic Functions by a Novel Variant of Hepatocyte Nuclear Factor 4γ

Hepatocyte nuclear factor 4α (HNF4α) is a critical factor for hepatocyte differentiation. HNF4α expression is decreased in hepatocellular carcinoma (HCC), which suggests a role in repression of hepatocyte dedifferentiation. In the present study, hepatic expression of HNF4γ was increased in liver-spe...

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Veröffentlicht in:	Molecular and cellular biology 2018-12, Vol.38 (24)
Hauptverfasser:	Sasaki, Shota, Urabe, Mizuho, Maeda, Tsukasa, Suzuki, Junko, Irie, Ryota, Suzuki, Masanori, Tomaru, Yasuhiro, Sakaguchi, Masakiyo, Gonzalez, Frank J., Inoue, Yusuke
Format:	Artikel
Sprache:	eng
Schlagworte:	hepatocellular carcinoma HNF4γ redifferentiation Spotlight transactivation
Online-Zugang:	Volltext
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