A phase I trial of oncolytic adenovirus ICOVIR-5 administered intravenously to melanoma patients

Oncolytic viruses represent a unique type of agents that combine self-amplification, lytic and immunostimulatory properties against tumors. A local and locoregional clinical benefit has been demonstrated upon intratumoral injections of an oncolytic herpes virus in melanoma patients, leading to its a...

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Veröffentlicht in:Human gene therapy. Clinical development 2018-09, Article humc.2018.107
Hauptverfasser: Garcia, Margarita, Moreno, Rafael, Gil, Marta, Cascallo, Manel, de Olza, Maria Ochoa, Cuadra, Carmen, Piulat, Josep Maria, Navarro, Valentin, Domenech, Marta, Alemany, Ramon, Salazar, Ramon
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Sprache:eng
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