Taurine exhibits an apoptosis-inducing effect on human nasopharyngeal carcinoma cells through PTEN/Akt pathways in vitro

Nasopharyngeal carcinoma (NPC) is a distinctive type of head and neck malignancy with a high incidence in southern China. Previous studies have confirmed that taurine shows an anti-cancer effect on a variety of human tumors by inhibiting cell proliferation and inducing apoptosis. However, the underl...

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Veröffentlicht in:	Amino acids 2018-12, Vol.50 (12), p.1749-1758
Hauptverfasser:	He, Feng, Ma, Ning, Midorikawa, Kaoru, Hiraku, Yusuke, Oikawa, Shinji, Zhang, Zhe, Huang, Guangwu, Takeuchi, Kazuhiko, Murata, Mariko
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Analytical Chemistry Anticancer properties Apoptosis Apoptosis - drug effects BAX protein bcl-2-Associated X Protein - metabolism Bcl-x protein bcl-X Protein - metabolism Biochemical Engineering Biochemistry Biomedical and Life Sciences Cancer Caspase Caspase 9 - metabolism Caspase-9 Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - drug effects China Chromosome 10 Colonies Deactivation Endoplasmic reticulum Flow cytometry Head Heat-Shock Proteins - metabolism Homology Humans Kinases Life Sciences Malignancy Mitochondria Nasopharyngeal carcinoma Nasopharyngeal Carcinoma - metabolism Nasopharyngeal Neoplasms - metabolism Neck Neurobiology Original Article p53 Protein Proteins Proteomics Proto-Oncogene Proteins c-akt - metabolism PTEN Phosphohydrolase - metabolism PTEN protein Taurine Taurine - pharmacology Tensin Throat cancer Tumors
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