Decorporation of thorium-228 from the rat by 3,4,3-LIHOPO and DTPA after simulated wound contamination

1 With DTPA as a comparison, the siderophore analogue 3,4,3-LIHOPO has been examined for its ability to remove 228Th nitrate from the rat after subcutaneous (sc) and intramuscular (im) injection to simulate wound contamination. The commencement of treat ment was delayed 30 min, 6 h or 1 d and the an...

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Veröffentlicht in:	Human & experimental toxicology 1995-02, Vol.14 (2), p.165-169
Hauptverfasser:	Stradling, G.N., Gray, S.A., Pearce, M.J., Wilson, I., Moody, J.C., Burgada, R., Durbin, P.W., Raymond, K.N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aza Compounds - administration & dosage Aza Compounds - pharmacology Biological and medical sciences Biological effects of radiation Disease Models, Animal Female Fundamental and applied biological sciences. Psychology Injections, Intramuscular Injections, Intraperitoneal Injections, Subcutaneous Kinetics Ligands Pentetic Acid - administration & dosage Pentetic Acid - pharmacology Pyridones - administration & dosage Pyridones - pharmacology Radiocontamination Rats Thorium Compounds - administration & dosage Thorium Compounds - metabolism Thorium Compounds - toxicity Tissues, organs and organisms biophysics Wound Healing - drug effects
Online-Zugang:	Volltext
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