A Case of Fatal Endrin Poisoning
1 Ingestion of 12 g of endrin by a 49-year-old man caused convulsions persisting for 4 days, hypersalivation, hyperthermia, renal insufficiency, thrombocytopenia and recurrent hypotension. Death followed after 11 days, due to pulmonary complications (infection and haemorrhage) and hypoxaemia causing...
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| Veröffentlicht in: | Human & experimental toxicology 1985-05, Vol.4 (3), p.241-247 |
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| container_title | Human & experimental toxicology |
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| creator | Runhaar, E.A. Sangster, B. Greve, P.A. Voortman, M. |
| description | 1 Ingestion of 12 g of endrin by a 49-year-old man caused convulsions persisting for 4 days, hypersalivation, hyperthermia, renal insufficiency, thrombocytopenia and recurrent hypotension. Death followed after 11 days, due to pulmonary complications (infection and haemorrhage) and hypoxaemia causing bradycardia and cardiac arrest.
2 Endrin and dieldrin concentrations in blood 4 hours, 6 and 11 days after ingestion were respectively 450, 86 and 71 μg/l for endrin and 60, 19 and 19 μg/l for dieldrin. Dieldrin was also present, possibly because the endrin preparation contained traces of dieldrin.
3 Endrin concentrations 11 days after ingestion were 0.071 mg/l in blood, in adipose tissue 89.5 mg/kg, in the heart 0.87 mg/kg, in the brain 0.89 mg/kg, in the kidneys 0.55 mg/kg and in the liver 1.32 mg/kg. |
| doi_str_mv | 10.1177/096032718500400303 |
| format | Article |
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2 Endrin and dieldrin concentrations in blood 4 hours, 6 and 11 days after ingestion were respectively 450, 86 and 71 μg/l for endrin and 60, 19 and 19 μg/l for dieldrin. Dieldrin was also present, possibly because the endrin preparation contained traces of dieldrin.
3 Endrin concentrations 11 days after ingestion were 0.071 mg/l in blood, in adipose tissue 89.5 mg/kg, in the heart 0.87 mg/kg, in the brain 0.89 mg/kg, in the kidneys 0.55 mg/kg and in the liver 1.32 mg/kg.</description><identifier>ISSN: 0144-5952</identifier><identifier>ISSN: 0960-3271</identifier><identifier>DOI: 10.1177/096032718500400303</identifier><identifier>PMID: 4007887</identifier><identifier>CODEN: HUTODJ</identifier><language>eng</language><publisher>Thousand Oaks, CA: SAGE Publications</publisher><subject>Biological and medical sciences ; Endrin - metabolism ; Endrin - poisoning ; Humans ; Hydrocarbons, Chlorinated - metabolism ; Liver Function Tests ; Male ; Medical sciences ; Middle Aged ; Pesticides, fertilizers and other agrochemicals toxicology ; Seizures - chemically induced ; Suicide ; Toxicology</subject><ispartof>Human & experimental toxicology, 1985-05, Vol.4 (3), p.241-247</ispartof><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-ebf8f527671f399b148afc03f0386d2dbff0de8974edf73ec2ad3f566df2c17e3</citedby><cites>FETCH-LOGICAL-c468t-ebf8f527671f399b148afc03f0386d2dbff0de8974edf73ec2ad3f566df2c17e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/096032718500400303$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/096032718500400303$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9272518$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4007887$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Runhaar, E.A.</creatorcontrib><creatorcontrib>Sangster, B.</creatorcontrib><creatorcontrib>Greve, P.A.</creatorcontrib><creatorcontrib>Voortman, M.</creatorcontrib><title>A Case of Fatal Endrin Poisoning</title><title>Human & experimental toxicology</title><addtitle>Hum Toxicol</addtitle><description>1 Ingestion of 12 g of endrin by a 49-year-old man caused convulsions persisting for 4 days, hypersalivation, hyperthermia, renal insufficiency, thrombocytopenia and recurrent hypotension. Death followed after 11 days, due to pulmonary complications (infection and haemorrhage) and hypoxaemia causing bradycardia and cardiac arrest.
2 Endrin and dieldrin concentrations in blood 4 hours, 6 and 11 days after ingestion were respectively 450, 86 and 71 μg/l for endrin and 60, 19 and 19 μg/l for dieldrin. Dieldrin was also present, possibly because the endrin preparation contained traces of dieldrin.
3 Endrin concentrations 11 days after ingestion were 0.071 mg/l in blood, in adipose tissue 89.5 mg/kg, in the heart 0.87 mg/kg, in the brain 0.89 mg/kg, in the kidneys 0.55 mg/kg and in the liver 1.32 mg/kg.</description><subject>Biological and medical sciences</subject><subject>Endrin - metabolism</subject><subject>Endrin - poisoning</subject><subject>Humans</subject><subject>Hydrocarbons, Chlorinated - metabolism</subject><subject>Liver Function Tests</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pesticides, fertilizers and other agrochemicals toxicology</subject><subject>Seizures - chemically induced</subject><subject>Suicide</subject><subject>Toxicology</subject><issn>0144-5952</issn><issn>0960-3271</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEURbNQaq3-AUGYhbgbm-9klqW0KhR0oeuQyUeZMk1q0ln474106EZw9eC9c--DA8Adgk8ICTGHDYcECyQZhBRCAskFmEJEac0ahq_Adc67si4onYBJIYSUYgqqRbXU2VXRV2t91H21CjZ1oXqPXY6hC9sbcOl1n93tOGfgc736WL7Um7fn1-ViUxvK5bF2rZeeYcEF8qRpWkSl9gYSD4nkFtvWe2idbAR11gviDNaWeMa59dgg4cgMPJ56Dyl-DS4f1b7LxvW9Di4OWWEEhWCMFxCfQJNizsl5dUjdXqdvhaD6VaH-qiih-7F9aPfOniOjh3J_GO86G937pIPp8hlrsMAMyYLNT1jWW6d2cUihOPnv8Q9WdnL1</recordid><startdate>198505</startdate><enddate>198505</enddate><creator>Runhaar, E.A.</creator><creator>Sangster, B.</creator><creator>Greve, P.A.</creator><creator>Voortman, M.</creator><general>SAGE Publications</general><general>Macmillan</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>198505</creationdate><title>A Case of Fatal Endrin Poisoning</title><author>Runhaar, E.A. ; Sangster, B. ; Greve, P.A. ; Voortman, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c468t-ebf8f527671f399b148afc03f0386d2dbff0de8974edf73ec2ad3f566df2c17e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Biological and medical sciences</topic><topic>Endrin - metabolism</topic><topic>Endrin - poisoning</topic><topic>Humans</topic><topic>Hydrocarbons, Chlorinated - metabolism</topic><topic>Liver Function Tests</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pesticides, fertilizers and other agrochemicals toxicology</topic><topic>Seizures - chemically induced</topic><topic>Suicide</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Runhaar, E.A.</creatorcontrib><creatorcontrib>Sangster, B.</creatorcontrib><creatorcontrib>Greve, P.A.</creatorcontrib><creatorcontrib>Voortman, M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Human & experimental toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Runhaar, E.A.</au><au>Sangster, B.</au><au>Greve, P.A.</au><au>Voortman, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case of Fatal Endrin Poisoning</atitle><jtitle>Human & experimental toxicology</jtitle><addtitle>Hum Toxicol</addtitle><date>1985-05</date><risdate>1985</risdate><volume>4</volume><issue>3</issue><spage>241</spage><epage>247</epage><pages>241-247</pages><issn>0144-5952</issn><issn>0960-3271</issn><coden>HUTODJ</coden><abstract>1 Ingestion of 12 g of endrin by a 49-year-old man caused convulsions persisting for 4 days, hypersalivation, hyperthermia, renal insufficiency, thrombocytopenia and recurrent hypotension. Death followed after 11 days, due to pulmonary complications (infection and haemorrhage) and hypoxaemia causing bradycardia and cardiac arrest.
2 Endrin and dieldrin concentrations in blood 4 hours, 6 and 11 days after ingestion were respectively 450, 86 and 71 μg/l for endrin and 60, 19 and 19 μg/l for dieldrin. Dieldrin was also present, possibly because the endrin preparation contained traces of dieldrin.
3 Endrin concentrations 11 days after ingestion were 0.071 mg/l in blood, in adipose tissue 89.5 mg/kg, in the heart 0.87 mg/kg, in the brain 0.89 mg/kg, in the kidneys 0.55 mg/kg and in the liver 1.32 mg/kg.</abstract><cop>Thousand Oaks, CA</cop><pub>SAGE Publications</pub><pmid>4007887</pmid><doi>10.1177/096032718500400303</doi><tpages>7</tpages></addata></record> |
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| ispartof | Human & experimental toxicology, 1985-05, Vol.4 (3), p.241-247 |
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| language | eng |
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| source | SAGE Complete A-Z List; MEDLINE; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Endrin - metabolism Endrin - poisoning Humans Hydrocarbons, Chlorinated - metabolism Liver Function Tests Male Medical sciences Middle Aged Pesticides, fertilizers and other agrochemicals toxicology Seizures - chemically induced Suicide Toxicology |
| title | A Case of Fatal Endrin Poisoning |
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