Metabolism and pharmacokinetics of genipin and geniposide in rats

Geniposide, an iridoid glucoside, is a major constituent in the fruits of Gardenia jasminoides (Gardenia fruits), a popular Chinese herb. Genipin, the aglycone of geniposide, is used to prepare blue colorants in food industry and also a crosslinking reagent for biological tissue fixation. In this st...

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Veröffentlicht in:	Food and chemical toxicology 2008-08, Vol.46 (8), p.2764-2769
Hauptverfasser:	Hou, Y.C., Tsai, S.Y., Lai, P.Y., Chen, Y.S., Chao, P.D.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals Biological and medical sciences Calibration Chemical Phenomena Chemistry, Physical Cholagogues and Choleretics - metabolism Cholagogues and Choleretics - pharmacokinetics Cholagogues and Choleretics - toxicity Chromatography, High Pressure Liquid Data Interpretation, Statistical Gardenia Gardenia - chemistry Gardenia jasminoides Genipin Geniposide glucosides Hydrolysis Injections, Intravenous Iridoid Glycosides Iridoids - metabolism Iridoids - pharmacokinetics Iridoids - toxicity Male Medical sciences medicinal plants metabolism mortality oral administration Pharmacokinetics Plant Extracts - chemistry Plant Extracts - pharmacokinetics Rats Rats, Sprague-Dawley Reproducibility of Results Toxicity Toxicology
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