An Afg2/Spaf-Related Cdc48-like AAA ATPase Regulates the Stability and Activity of the C. elegans Aurora B Kinase AIR-2

The Aurora B kinase is the enzymatic core of the chromosomal passenger complex, which is a critical regulator of mitosis. To identify novel regulators of Aurora B, we performed a genome-wide screen for suppressors of a temperature-sensitive lethal allele of the C. elegans Aurora B kinase AIR-2. This...

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Veröffentlicht in:	Developmental cell 2008-10, Vol.15 (4), p.603-616
Hauptverfasser:	Heallen, Todd R, Adams, Henry P, Furuta, Tokiko, Verbrugghe, Koen J, Schumacher, Jill M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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